If a patient with acute otitis media has a penicillin allergy, which medication may be prescribed?

In the context of treating acute otitis media in a patient with a penicillin allergy, Cefdinir is a suitable option. Cefdinir is a third-generation cephalosporin antibiotic that has activity against common pathogens responsible for acute otitis media, including Streptococcus pneumoniae and Haemophilus influenzae. It is considered safe for patients with a penicillin allergy, particularly if the allergy is non-severe, as the cross-reactivity between cephalosporins and penicillins is relatively low, but it is still important to practice caution.

Other listed options are less appropriate given the patient's allergy. Augmentin contains amoxicillin and would be contraindicated due to the penicillin allergy. Ceftriaxone, also a cephalosporin, could be used in some cases, but it is typically reserved for more severe infections or those requiring parenteral therapy. Amoxicillin, being a penicillin derivative, should be completely avoided in a patient with a penicillin allergy. Thus, prescribing Cefdinir aligns with the need to treat the infection while also considering the safety of the patient based on their allergy status.