What is the diagnosis for a child presenting with mild fever, URI symptoms, decreased appetite, and vesicular lesions in the oral cavity, followed by an exanthem 1-2 days later?

The presentation of mild fever, upper respiratory infection (URI) symptoms, decreased appetite, and the presence of vesicular lesions in the oral cavity that is followed by an exanthem is characteristic of hand, foot, and mouth disease. This viral illness, commonly caused by enteroviruses such as coxsackievirus, typically affects younger children.

Initially, the child may exhibit non-specific symptoms such as fever and malaise, followed by the development of painful vesicular lesions in the mouth. The exanthem usually appears shortly after the oral lesions, often on the hands and feet, and may also manifest on the buttocks or other areas of the body. The pattern of symptoms aligns well with hand, foot, and mouth disease, making it the most likely diagnosis in this scenario.

Other options present different clinical features or would not typically align with the described symptomatology. Herpangina also features oral lesions but is more commonly associated with severe throat pain and does not typically lead to a widespread rash. An aplastic crisis usually pertains to patients with underlying hematological issues and is not described with oral vesicles or an exanthem. Mumps, while presenting with fever, can lead to parotitis and other systemic symptoms, but it does