Which condition is characterized by sloughing of less than 10% body surface area?

Stevens-Johnson Syndrome (SJS) is characterized by sloughing of less than 10% of the total body surface area. This condition, often triggered by medications or infections, leads to a painful rash that can cause blistering and detachment of the epidermis. The damage involves mucosal surfaces, including the eyes, mouth, and genitals, in addition to the skin.

The distinction of SJS primarily lies in its less extensive nature compared to Toxic Epidermal Necrolysis (TEN), which typically involves more than 30% of the body surface area. Erythema multiforme major, while also presenting with skin lesions and sometimes involving mucous membranes, is defined by a different severity and presentation. Lastly, urticaria, commonly known as hives, does not usually lead to extensive skin sloughing and is typically characterized by wheals and itching rather than full-thickness skin loss.

Understanding these distinctions is essential for accurate diagnosis and management in clinical settings, highlighting the significance of recognizing the percentage of affected body surface area in conditions involving severe skin reactions.